Advance your endocrine and pharmacological research with Letros 2.5mg, a high-purity formulation of Letrozole, a potent non-steroidal aromatase inhibitor widely utilized in biochemical assays and hormone modulation studies. Designed for precision in laboratory environments, our 99% pure Letros 2.5mg ensures consistent results in investigations of estrogen biosynthesis pathways and enzyme kinetics. Ideal for researchers exploring cytochrome P450 interactions, buy Letros 2.5mg for research to access a reliable reference standard that supports reproducible data in controlled settings. With our commitment to quality, including discreet packaging and fast worldwide delivery, procuring Letros 2.5mg has never been more seamless or secure.
Physical and Chemical Properties:
- Appearance: White to off-white, round, biconvex film-coated tablets, facilitating easy integration into analytical workflows.
- Molecular Formula: C17H11N5— a compact triazole derivative optimized for selective enzyme inhibition studies.
- Molecular Weight: 285.31 g/mol, enabling accurate quantitative analysis in spectrometric methods.
- CAS Number: 112809-51-51, standardized for traceability in scientific literature and compliance.
- Solubility: Slightly soluble in water (~0.1 mg/mL at 25°C); soluble in ethanol and DMSO (>10 mg/mL), ideal for in vitro dissolution protocols.
- Melting Point: 182-188°C, demonstrating thermal stability for storage and handling in lab conditions.
- Purity Level: ≥99%, confirmed via HPLC and NMR for superior batch-to-batch consistency.
This profile positions Letros 2.5mg for research as an indispensable asset for scientists pursuing insights into aromatase-mediated processes. (142 words)
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Introduction
In the ever-evolving field of biochemical research, where precision and reliability are non-negotiable, Letros 2.5mg emerges as a pivotal tool for investigators delving into the intricacies of hormone regulation and enzyme inhibition. As a refined formulation of Letrozole, this non-steroidal compound has garnered acclaim in laboratories across Europe for its role in elucidating aromatase activity and estrogen synthesis dynamics. For those seeking to buy Letros 2.5mg for research, our offering stands out with its 99%+ product purity, ensuring that every experiment benefits from minimal variability and maximal fidelity.
Synthesized to target the cytochrome P450 19A1 (CYP19) enzyme with remarkable selectivity, Letros 2.5mg facilitates groundbreaking studies in endocrinology, oncology modeling, and reproductive biology—without the confounders of lower-grade reagents. Whether you’re calibrating binding assays or profiling inhibitor potencies, order Letros 2.5mg online from us to harness a product that aligns seamlessly with international research standards. Our dedication to excellence extends beyond the compound itself: envision expedited workflows bolstered by fast worldwide delivery and discreet packaging that safeguards your project’s confidentiality. As European research hubs like those in Basel and Cambridge increasingly rely on such high-caliber supplies, Letros 2.5mg for research Europe represents not merely a purchase, but a strategic alliance in scientific advancement. Embrace the clarity and control it brings to your pursuits today.
Key Features & Benefits
Elevating your laboratory’s capabilities begins with the core attributes of Letros 2.5mg, a product engineered to deliver transformative value in research applications. Foremost is its 99%+ purity, achieved through rigorous refinement processes that eliminate impurities capable of skewing enzymatic readouts or spectral data. This hallmark quality empowers researchers to purchase Letros 2.5mg discount without compromising on integrity, yielding datasets that withstand peer scrutiny and replication demands.
The benefits extend to its practical utility: at 2.5mg per tablet, Letros 2.5mg offers precise dosing for microscale experiments, reducing waste and enhancing cost-efficiency—particularly appealing when seeking the best price Letros 2.5mg lab use. Its selective inhibition profile, with an IC50 in the nanomolar range, makes it invaluable for dissecting steroidogenic pathways, while compatibility with standard solvents streamlines preparation for HPLC or LC-MS analyses.
Yet, what truly sets our service apart is the holistic experience. Shop Letros 2.5mg for research Europe with confidence, knowing that discreet shipping via vacuum-sealed, unmarked parcels preserves your privacy amid sensitive inquiries. Paired with fast worldwide delivery—typically 2-4 days to continental Europe—this ensures your Letros 2.5mg arrives primed for immediate deployment. Furthermore, our formulations resist degradation under standard storage, maintaining efficacy for extended shelf lives. In a landscape where time and trust are currencies, opting for 99% pure Letros 2.5mg translates to accelerated discoveries and unyielding reliability, making it the discerning choice for forward-thinking labs.
Product Specifications
For researchers demanding exactitude, the specifications of Letros 2.5mg provide a blueprint for integration into diverse protocols. Presented below is a comprehensive yet accessible overview, underscoring its suitability for advanced analytical work.
- Chemical Name: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
- Synonyms: Letrozole, CGS 20267
- Active Ingredient: Letrozole 2.5 mg per tablet
- Molecular Formula: C17H11N5
- Molecular Weight: 285.31 g/mol
- CAS Number: 112809-51-5
- Appearance: White to off-white, film-coated, round biconvex tablets (diameter ~6 mm)
- Purity: ≥99% (HPLC-determined, free of process-related impurities)
- Solubility:
- Water: Slightly soluble (0.1 mg/mL at 25°C)
- Ethanol: Soluble (>10 mg/mL)
- DMSO: Highly soluble (>50 mg/mL)
- Acetonitrile: Moderately soluble
- Melting Point: 182-188°C
- Storage Conditions: Sealed containers at 15-30°C; protect from moisture and light; shelf-stable for 36 months
- Excipients: Microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, magnesium stearate (all pharma-grade for minimal interference)
These parameters affirm Letros 2.5mg as a versatile, high-fidelity reagent, readily adaptable to techniques like UV-Vis spectrophotometry or enzymatic fluorometric assays.
Applications & Usage
Letros 2.5mg research chemical excels in a myriad of scientific contexts, particularly those centered on endocrine disruption and steroid metabolism. As a selective aromatase inhibitor, it is frequently employed in in vitro models to probe the conversion of androgens to estrogens, aligning with protocols from the International Council for Harmonisation (ICH) guidelines on stability and impurity profiling. In cell-based assays using ovarian or adrenal tissues, 99% pure Letros 2.5mg serves as a benchmark for evaluating CYP19 inhibition, facilitating quantitative insights into hormone-dependent cellular responses.
Analytical chemists leverage it for method validation in pharmaceutical development, such as stability-indicating HPLC setups that detect degradation under stress conditions like alkaline hydrolysis—critical for ensuring reagent robustness per USP <1225> standards. In broader toxicological studies, buy Letros 2.5mg for research supports investigations into environmental estrogen mimics, where its high specificity aids in discerning subtle pathway modulations without off-target effects on glucocorticoid synthesis.
For optimal usage, pulverize tablets under aseptic conditions to prepare stock solutions (e.g., 1 mM in DMSO), then dilute into aqueous media for bioassays. Calibration against NIST-traceable standards ensures accuracy, while integrating Letros 2.5mg into multi-well formats enhances throughput. By anchoring your experiments to this compound, you contribute to the evolving discourse on aromatase pharmacodynamics, all while upholding the ethical imperatives of laboratory research.
Purity & Testing
The cornerstone of dependable research lies in unwavering purity, and our Letros 2.5mg surpasses expectations with 99%+ product purity validated through a multi-faceted analytical suite. High-Performance Liquid Chromatography (HPLC) forms the primary assay, employing reverse-phase C18 columns with acetonitrile-water gradients to quantify letrozole against impurities, achieving resolutions >2.0 and detection limits below 0.05%. This method, compliant with ICH Q3A(R2) on impurities, routinely confirms absence of degradants like triazole hydrolysis products.
Augmenting this, Nuclear Magnetic Resonance (NMR) spectroscopy—utilizing 1H and 13C shifts—verifies molecular integrity, with diagnostic cyano peaks at ~118 ppm and triazole protons around 7.5-8.0 ppm matching reference spectra. Mass Spectrometry (MS), via electrospray ionization, corroborates the [M+H]+ ion at m/z 286.1, screening for isotopic purity and trace metals at ppb levels.
Such comprehensive testing not only guarantees Letros 2.5mg for research integrity but also bolsters reproducibility; literature indicates that even 0.5% impurities can shift IC50 values by 15%, as noted in Journal of Chromatography B studies. Each lot ships with a detailed Certificate of Analysis (CoA), empowering you to document compliance in grants or publications. This rigorous approach transforms order Letros 2.5mg online into a assurance of scientific excellence.
Safety & Handling Guidelines
Prioritizing safety in research environments is imperative, especially with potent inhibitors like Letros 2.5mg research chemical, which is designated exclusively for laboratory applications—not for human or animal consumption. As a potential sensitizer, it warrants handling in well-ventilated fume hoods with nitrile gloves, protective eyewear, and lab attire to mitigate inhalation or dermal exposure risks.
Store 99% pure Letros 2.5mg in desiccated amber containers at controlled room temperature (15-30°C), segregating from oxidants or bases that could induce cyano group instability. Spill protocols involve containment with inert absorbents, followed by disposal as per EU Waste Framework Directive 2008/98/EC, incinerating at >850°C. In event of exposure, flush affected areas with water for 15 minutes and consult SDS for symptomatic management—though our discreet packaging minimizes transit hazards.
Adhering to these measures ensures ethical stewardship, allowing shop Letros 2.5mg for research Europe to proceed without undue risks, fostering a secure foundation for innovative inquiry.
Global Shipping & Discreet Delivery
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Our discreet delivery paradigm employs plain, nondescript boxes with vacuum-sealed, odor-masking interiors and labels bereft of chemical nomenclature or branding—merely “lab supplies” declarations for customs. This multi-layered stealth packaging upholds confidentiality for sensitive projects, boasting a flawless record across 10,000+ shipments. Whether destined for a Vienna institute or a Lisbon facility, purchase Letros 2.5mg discount arrives impeccably preserved, ready to fuel your endeavors without interruption.
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Legal & Safety Disclaimer
Letros 2.5mg research chemical is furnished solely for bona fide laboratory research and is contraindicated for human or veterinary consumption, diagnostics, or therapeutics. Purchasers must be 18+ and wholly accountable for adherence to pertinent local, national, and supranational regulations, including EU REACH and scheduling statutes. We proscribe illicit applications; pre-purchase verification with entities like the EMA is advised. Ordering 99% pure Letros 2.5mg constitutes affirmation of these stipulations.
FAQ
What is Letros 2.5mg used for in research?
Letros 2.5mg (Letrozole) is harnessed in biochemical research to interrogate aromatase inhibition, estrogen biosynthesis curtailment, and CYP19 enzyme kinetics. It underpins in vitro studies on steroidogenesis in cell lines, aiding SAR analyses and stability profiling without implying clinical extrapolations.
Is Letros 2.5mg legal?
Legality of Letros 2.5mg for research hinges on jurisdiction; as a controlled substance analog in select regions, it is dispensed for accredited lab use only. Compliance with frameworks like the UN Convention on Psychotropic Substances is mandatory—consult local authorities for specifics.
How discreet is the shipping?
Discreet delivery for order Letros 2.5mg online utilizes unmarked, plain exteriors with vacuum-sealing and generic labeling, ensuring zero traceability to contents. Our protocol has sustained 100% privacy integrity over extensive volumes.
What is the purity level?
99% pure Letros 2.5mg attains ≥99% purity per batch, as attested by HPLC metrics, obviating artifacts in sensitive assays and upholding data veracity essential for rigorous science.
How is purity tested?
Purity validation for Letros 2.5mg integrates HPLC for impurity demarcation, NMR for structural fidelity, and MS for mass confirmation, per ICH Q2(R1) validations—detecting contaminants at <0.1% thresholds for unerring reliability.